TEM image of transverse colon. A. The ultrastructure of the crypt in the No-, AEtLP-, Lop + vehicle-, and Lop + AEtLP-treated group was viewed by TEM at x1800 or x3000 magnification. B. Diameter of crypt lumen (a), the number of paneth cells (b) and lipid droplets (c) were measured using Leica Application Suite (Leica Microsystems, Switzerland). Five to six rats per group were assayed in triplicate by TEM analysis. Data represent the mean ± SD from three replicates. a, p < 0.05 compared to the No-treated group. b, p < 0.05 compared to the AEtLP-treated group. c, p < 0.05 compared to the Lop + vehicle-treated group. Lm, lumen of crypt; Gb, goblet cells; Pn, paneth cells; Gr, granule cells; Ld, lipid droplets; Nu, nucleus; Mt, mitochondria.