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Table 4 Effect of paracetamol and protective treatments at ALT, AST and ALP (U/L)

From: Methanol extract of Melastoma malabathricum leaves exerted antioxidant and liver protective activity in rats

Treatment Dose (mg/kg) ALT (U/L) AST (U/L) ALP (U/L)
Control - 15.8 ± 2.9 95.1 ± 5.9 115.6 ± 7.0
10% DMSO + Paracetamol - 1714.0 ± 142.2a 2266.0 ± 140.4a 345.8 ± 39.3a
Silymarin + Paracetamol 200 693.4 ± 162.5ab 651.2 ± 141.1ab 190.0 ± 9.6ab
MEMM + Paracetamol 50 1453.0 ± 125.9a 2200.7 ± 247.0a 384.0 ± 43.8a
250 1308.0 ± 184.1ab 1719.0 ± 160.7ab 217.2 ± 17.2ab
  500 979.5 ± 174.0ab 1458.0 ± 271.2ab 178.2 ± 33.9ab
  1. a Data with this superscript differed significantly (P < 0.05) when compared to the normal control value in the respective column.
  2. b Data with this superscript differed significantly (P < 0.05) when compared to the 10% DMSO + Paracetamol-treated group in the respective column.
  3. Values are expressed as means ± S.E.M. of six replicates.