Methanol extract of Melastoma malabathricum leaves exerted antioxidant and liver protective activity in rats

Table 4 Effect of paracetamol and protective treatments at ALT, AST and ALP (U/L)

Treatment	Dose (mg/kg)	ALT (U/L)	AST (U/L)	ALP (U/L)
Control	-	15.8 ± 2.9	95.1 ± 5.9	115.6 ± 7.0
10% DMSO + Paracetamol	-	1714.0 ± 142.2^a	2266.0 ± 140.4^a	345.8 ± 39.3^a
Silymarin + Paracetamol	200	693.4 ± 162.5^ab	651.2 ± 141.1^ab	190.0 ± 9.6^ab
MEMM + Paracetamol	50	1453.0 ± 125.9^a	2200.7 ± 247.0^a	384.0 ± 43.8^a
MEMM + Paracetamol	250	1308.0 ± 184.1^ab	1719.0 ± 160.7^ab	217.2 ± 17.2^ab
	500	979.5 ± 174.0^ab	1458.0 ± 271.2^ab	178.2 ± 33.9^ab

^a Data with this superscript differed significantly (P < 0.05) when compared to the normal control value in the respective column.
^b Data with this superscript differed significantly (P < 0.05) when compared to the 10% DMSO + Paracetamol-treated group in the respective column.
Values are expressed as means ± S.E.M. of six replicates.

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