Methanol extract of Melastoma malabathricum leaves exerted antioxidant and liver protective activity in rats

Table 2 Effect of MEMM on the body and liver weights following treatment of rats against paracetamol

Treatment	Dose (mg/kg)	Body weight (BW) (g)	Liver weight (LW) (g)	LW/BW (%)
Control	-	211.0 ± 2.7	5.9 ± 0.3	2.9 ± 0.1
10% DMSO + Paracetamol	-	207.9 ± 3.6	8.7 ± 0.3^a	4.9 ± 0.4^a
Silymarin + Paracetamol	200	202.1 ± 2.6	6.9 ± 0.2^ab	3.6 ± 0.1^ab
MEMM + Paracetamol	50	203.5 ± 5.4	8.9 ± 0.2^a	4.4 ± 0.1^a
MEMM + Paracetamol	250	193.6 ± 4.1^ab	7.7 ± 0.1^ab	4.6 ± 0.1^a
	500	180.1 ± 3.9^ab	6.2 ± 0.9^b	3.8 ± 0.2^ab

^a Data with this superscript differed significantly (P < 0.05) when compared to the normal control value in the respective column.
^b Data with this superscript differed significantly (P < 0.05) when compared to the 10% DMSO + Paracetamol-treated group in the respective column.
Values are expressed as means ± S.E.M. of six replicates.

ISSN: 2662-7671