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Table 8 Cytotoxic activity (IC 50 μg/ml) of fractions obtained from the rhizome chloroform extract

From: Cytotoxic effect of Alpinia scabra (Blume) Náves extracts on human breast and ovarian cancer cells

Fraction IC50 a(μg/ml)(SIb)
SKOV-3 MRC-5
RC1 94.56 ± 4.32 95.70 ± 3.00
RC2 88.90 ± 4.78 66.00 ± 5. 66
RC3 25.49 ± 2.56 50.80 ± 1.24
RC4 23.35 ± 2.24 71.00 ± 3.40
RC5 2.84 ± 0.60 (14.15) 40.20 ± 1.50
RC6 39.90 ± 1.18 >100
RC7 32.63 ± 6.78 >100
RC8 50.24 ± 7.78 >100
RC9 64.50 ± 1.40 >100
RC10 66.82 ± 2.26 >100
RC11 51.30 ± 3.12 >100
RC12 45.70 ± 4.00 >100
RC13 21.60 ± 10.80 >100
RC14 29.70 ± 2.50 >100
RC15 25.33 ± 3.56 >100
RC16 24.75 ± 2.85 >100
RC17 45.08 ± 3.45 >100
RC18 43.89 ± 4.76 >100
Chloroform 17.33 ± 0.58 (2.6) 44.65 ± 2.57
  1. aData are presented as mean ± SD from three independent experiments triplicate for each. Values in bold characters are considered to have cytotoxic activity (IC5020 μg/ml or less); bSelectivity Index (SI).