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Table 7 Cytotoxic activity (IC 50 μg/ml) of fractions and sub-fraction obtained from leaf chloroform extract

From: Cytotoxic effect of Alpinia scabra (Blume) Náves extracts on human breast and ovarian cancer cells

Fraction (LC)/Sub-fraction (VLC)

IC50 a(μg/ml)

MRC-5

MCF7

SKOV-3

LC1

50.00 ± 5.00

92.30 ± 4.78

>100

LC2

42.20 ± 4.48

56.00 ± 6.60

>100

LC3

33.40 ± 4.05

40.50 ± 2.56

>100

LC4

18.53 ± 1.02

11.12 ± 0.24

>100

LC5

51.18 ± 4.56

39.18 ± 1.34

>100

LC6

>100

>100

>100

LC7

>100

>100

>100

LC8

>100

>100

>100

LC9

>100

>100

>100

LC10

>100

>100

>100

VLC9

15.53 ± 0.50

10.89 ± 0.64

>100

Chloroform

25.00 ± 0.00

14.67 ± 0.58

32.90 ± 0.76

  1. aData are presented as mean ± SD from three independent experiments triplicate for each. Values in bold characters are considered to have cytotoxic activity (IC5020 μg/ml or less).