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Table 6 Cytotoxic activity (IC 50 μg/ml) of A. scabra pseudo stem extracts

From: Cytotoxic effect of Alpinia scabra (Blume) Náves extracts on human breast and ovarian cancer cells

Extracts Treatment duration (hour) IC50 a(μg/ml) (SIb)
MCF7 SKOV-3 MRC-5
Methanol 24 >100 >100 >100
48 >100 >100 >100
72 >100 >100 >100
Hexane 24 >100 40.67 ± 3.51 >100
48 84.00 ± 1.00 34.00 ± 1.73 55.86 ± 16.71
72 67.30 ± 1.15 34.67 ± 0.58 49.74 ± 1.33
Chloroform 24 80.00 ± 15.10 56.00 ± 5.29 >100
48 66.67 ± 1.16 30.67 ± 5.13 52.86 ± 1.75
72 59.30 ± 1.15 33.00 ± 1.73 48.18 ± 2.34
Water 24 >100 >100 >100
48 >100 >100 >100
72 >100 >100 >100
Doxorubicinc 24 2.50 ± 0.10 2.50 ± 0.10 >100
48 2.37 ± 0.23 (32.4) 1.77 ± 0.15 (43.4) 76.87 ± 12.64
72 0.39 ± 0.02 (4.3) 1.47 ± 0.15 (1.1) 1.68 ± 0.42
  1. aData are presented as mean ± SD from three independent experiments triplicate for each. Values in bold characters are considered to have cytotoxic activity (IC5020 μg/ml or less); bSelectivity Index (SI); cPositive control.