Figure 6

The summary for the effects of naloxone, naloxonazine, naltrindole and nor -binaltorphimine on the 100 Hz EA-induced exacerbation of epileptic activities. Panel A depicts the results obtained from the dark period and panel B demonstrates the data acquired from the light period. The bars from the left to the right in both panels A and B represent the results obtained from the PFS + EA + pilocarpine group, naloxone + EA + pilocarpine group, naloxonazine + EA + pilocarpine group, naltrindole + EA + pilocarpine group and nor-binaltorphimine + EA + pilocarpine group. In panel C, the black circles represent the values obtained from the PFS + EA + pilocarpine group, the black triangles depict the results of the naloxone + EA + pilocarpine group, the white circles demonstrate the values obtained from the naloxonazine + EA + pilocarpine group, the white diamonds elucidate the results of the naltrindole + EA + pilocarpine group, and the white triangles indicate the data acquired from the nor-binaltorphimine + EA + pilocarpine group. **: p < 0.01 vs. the PFS + EA + pilocarpine group.