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Table 2 Analgesic effect of the different extracts of Cyperus rotundus on acetic acid-induced writhings

From: Pharmacological, antioxidant, genotoxic studies and modulation of rat splenocyte functions by Cyperus rotundus extracts

Treatment

Doses (mg/kg)

Acetic acid writhing contractiona

Percent inhibition (%)

Control

-

14 ± 0,70

-

Diclofenac sodium

25

10,33 ± 4,04

26,21

50

1,5 ± 0,7*

89,30

100

0 ± 0*

100

TOF enriched extract

50

5,4 ± 0,54*

61,42

150

3,2 ± 0,83*

77 ,2

300

1 ± 1*

92,8

Aqueous extract

50

11 ± 1,58*

21,5

150

8 ± 0,70*

42,9

300

4,8 ± 0,83*

65,7

Ethyl acetate extract

50

10 ± 2,73*

28,6

150

8,2 ± 1,92*

41,4

300

5,2 ± 1,30*

63

Methanolic extract

50

8 ± 2,88

10

150

11,2 ± 1,92*

20

 

300

8 ± 1*

43

  1. a Values are expressed as mean ± standard deviation (n = 5 animals). *P < 0,05 compared to corresponding control (Student’s t-test).