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Table 3 Total protein, TBARS, GSH, Nitrite & TNF α level in different groups

From: Attenuating effect of standardized fruit extract of punica granatum L in rat model of tibial and sural nerve transection induced neuropathic pain

Groups Total protein (mg/ml) TBARS (nmol/mg of protein) GSH (μg/mg of protein) Nitrite (μg/ml) TNF α level (pg/mg of protein)
Normal control 1.94 ± 0.25 2.87 ± 0.11 50.47 ± 3.21 26.35 ± 2.23 13.34 ± 1.54
Sham control 2.06 ± 0.34 3.07 ± 0.43 51.24 ± 3.05 28.23 ± 2.89 14.03 ±1.06
Vehicle in TST 2.13 ± 0.32 8.97 ± 0.41 27.56 ± 2.46 43.24 ± 2.56 66.14 ± 1.62
TST 2.44 ± 0.24 9.07 ±0.41a 28.14 ± 3.05a 44.04 ± 2.72a 67.11 ± 2.82a
PFE 300 mg/kg per se 2.11 ± 0.12 3.27 ± 0.12 50.22 ± 2.86 27.13 ± 1.87 12.44 ± 1.35
GABAPENTIN 100 mg/kg per se 2.17 ± 0.25 2.84 ± 0.49 50.66 ± 2.45 27.05 ± 1.43 12.57 ± 1.68
PFE 100 mg/kg + TST 2.67 ± 0.46 5.04 ± 0.53b 40.12 ± 2.55b 37.62 ± 2.54b 50.21 ± 2.51b
PFE 300 mg/kg + TST 2.21 ± 0.22 3.87 ± 0.38b 46.62 ± 2.33b 33.15 ± 2.39b 21.39 ±2.23b
BADGE + PFE 100 mg/kg + TST 2.49 ± 0.32 6.13 ± 0. 36c 33.61 ± 2.38c 38.18 ± 2.61c 57.62 ± 1.11c
BADGE + PFE 300 mg/kg + TST 2.16 ± 0.61 5.55 ± 0. 18d 38.12 ± 1.58d 35.16 ± 2.47d 38.01 ± 2.14d
BADGE + TST 2.43 ± 0.28 9.87 ± 0. 44a 54.67 ± 2.39a 46.86 ± 2.77a 68.41 ± 2.11a
L-NAME + TST 2.10 ± 0.53 6.95 ± 0. 14b 37.22 ± 3.04b 32.35 ± 2.23b 64.17 ± 2.22b
L-arginine + TST 2.58 ± 0.23 9.95 ± 0. 46a 25.28 ± 2.88a 48.61 ± 1.58a 66.31 ± 2.35a
L-NAME + PFE 100 mg/kg + TST 2.73 ± 0.18 5.01 ± 0.47b 39.17 ± 2.23b 35.96 ± 2.83b 51.89 ± 1.18b
L-NAME + PFE 300 mg/kg + TST 2.89 ± 0.29 3.75 ± 0. 23b 48.01 ± 1.06b 31.48 ± 2.98b 21.98 ± 2.21b
L-arginine + PFE 100 mg/kg + TST 2.93 ± 0.41 6.14 ± 0.11b 37.33 ± 2.81b 42.48 ± 2.14b 49.47 ± 2.36b
L-arginine + PFE 300 mg/kg + TST 2.34 ± 0.45 6.43 ± 0. 59e 36.83 ± 2.91e 35.36 ± 2.37e 22.08 ± 2.38e
GABAPENTIN 100 mg/kg + TST 2.09 ± 0.59 8.94 ± 0. 25 31.44 ± 2.33 30.15 ± 3.44b 62.16 ± 2.59
  1. a = P < 0.05 vs. sham control group.
  2. b = P < 0.05 vs. TST group.
  3. c = P < 0.05 vs. PFE 100 + TST.
  4. d = P < 0.05 vs. PFE 300 + TST.
  5. e = P < 0.05 vs. L-NAME + PFE (300 mg/kg) + TST.