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Table 4 Effect on antioxidant enzyme at end of the study

From: Umbelliferone β-D-galactopyranoside from Aegle marmelos (L.) corr. an ethnomedicinal plant with antidiabetic, antihyperlipidemic and antioxidative activity

S. No.

Biochemical parameter

Normal control

Normal control + UFG (40 mg/kg)

STZ-diabetic controla

STZ diabetes + UFD (10 mg/kg)b

STZ diabetes + UFD (20 mg/kg)b

STZ diabetes + UFD (40 mg/kg)b

STZ diabetes + glibenclamideb

1

SOD (U/mg of protein)

212.4 ± 2.839

213 ± 2.608

73.8 ± 4.005***

149.4 ± 5.391**

175.2 ± 3.353**

198.2 ± 3.247***

202.6 ± 3.776***

2

CAT (U/mg of protein)

135.8 ± 3.652

136.6 ± 3.894

60.8 ± 1.562***

85 ± 3.286*

97.8 ± 2.939**

130.2 ± 3.397***

129.2 ± 2.154***

3

GPx (nmole/mg of protein)

33.2 ± 2.267

34.2 ± 2.267

14 ± 0.836***

21 ± 0.707**

24.6 ± 0.872**

31.2 ± 1.068***

28.8 ± 0.811***

4

MDA (nmole/mg of protein)

0.241 ± 0.007

0.222 ± 0.009

0.522 ± 0.016***

0.396 ± 0.017*

0.312 ± 0.008**

0.274 ± 0.011***

0.261 ± 0.014***

  1. All values represent mean ± SEM * P < 0.05; ** P < 0.01; *** P < 0.001, ns < non significant; ANOVA, followed by Dunnett’s multiple comparison test.
  2. a Compared to vehicle control.
  3. b Compared to diabetic control.