Figure 22

Effect of umbelliferone β-D-galactopyranoside (UFG) on histopathology of kidney normal and STZ treated groups rat: (A) Normal control: Average size of glomerulus shown in the normal group rat histopathology. (B) Diabetic control: Inflammatory cells in blood vessels (blue arrow) and fat deposition (yellow arrow) shown in the histopathology of diabetic control group rat. (C) UFG I (10 mg/kg): Some inflammatory cell in blood vessels (blue arrow) and deposition of fat (yellow arrow) found in the histopathology of UFG I (10 mg/kg) treated groups’ rat. (D) UFG II (20 mg/kg): Only fat deposition (yellow arrow) shown in the histopathology of UFG II (20 mg/kg) treated group rat. (E) UFG III (40 mg/kg): Histopathology of dose UFG (40 mg/kg) treated group rat shown average size of glomerulrs but slightly bigger in size as compared to the normal control. (F) Glibenclamide (10 mg/kg): Histopathology of glibenclamide treated group animal shown the histopathology similar to the normal kidney. The samples were obtained from the same liver anatomical regions. For each group, 6 rats were examined and 80 pictures were taken. The above picture for each group was chosen randomly from the 80 pictures in this group. Original magnification, 40 × .