Figure 5

The concentration of BDNF in the hippocampus of rats that were handled and displayed temporal lobe epilepsy (TLE). TLE was induced by injecting rats intraperitoneally (i.p.) with pilocarpine (350 mg/kg). Thirty minutes prior to the pilocarpine injection, the animals were treated with atropine (1 mg/ kg, i.p.) to reduce peripheral pilocarpine effects. Results are the mean ± SEM of n = 4 rats per group. *** p < 0.001, Significantly different from Handled group respectively (Student’s t-test).