Groups | Doses | T1DM mice blood glucose levels(mmol/L) | Relative to model control (30thday) | T2DM rats blood glucose levels(mmol/L) | Relative to model control 30thday | ||||
---|---|---|---|---|---|---|---|---|---|
Day 0 | Day 15 | Day 30 | Day 0 | Day 15 | Day 30 | ||||
Normal control | 7.7 ± 1.2 | 6.7 ± 1.6 | 5.4 ± 2.3 | 5.7 ± 2.1 | 5.60 ± 0.28** | 3.91 ± 1.38** | |||
Model control | 52.1 ± 7.6 | 51.3 ± 10.4 | 42.6 ± 2.8 | 23.9 ± 6.6 | 19.77 ± 3.69 | 25.10 ± 0.61 | |||
Positive control | 62.5 ± 9.8 | 24.4 ± 4.9 | 10.4 ± 6.0** | ↓75.58% | 23.5 ± 4.8 | 14.04 ± 2.55** | 6.72 ± 1.57** | ↓73.22% | |
PH-TP | H | 54.6 ± 3.1 | 52.2 ± 1.6 | 37.9 ± 5.5* | ↓11.03% | 25.0 ± 2.4 | 18.69 ± 4.22c | 14.84 ± 2.41** | ↓40.87% |
M | 56.0 ± 2.4 | 51.8 ± 6.8 | 48.8 ± 7.1C | ↑14.55% | 24.2 ± 2.5 | 16.73 ± 2.95c | 16.67 ± 2.41** | ↓33.59% | |
L | 56.8 ± 2.8 | 50.1 ± 5.2 | 40.1 ± 5.3C | ↓5.87% | 23.4 ± 5.8 | 16.68 ± 2.69c | 12.95 ± 0.92** | ↓48.41% | |
PF40 | H | 52.9 ± 5.5 | 50.8 ± 4.3 | 37.5 ± 8.7* | ↓11.97% | 24.0 ± 5.7 | 15.78 ± 5.05* | 6.78 ± 5.47** | ↓72.99% |
M | 51.2 ± 4.1 | 49.4 ± 3.5 | 34.2 ± 8.0* | ↓19.72% | 25.2 ± 3.1 | 15.82 ± 3.67* | 11.41 ± 2.89** | ↓54.54% | |
L | 50.2 ± 6.3 | 47.6 ± 7.1 | 40.4 ± 7.3C | ↓5.16% | 23.3 ± 6.9 | 15.25 ± 1.95* | 12.80 ± 1.15** | ↓49.00% | |
PF60 | H | 52.8 ± 6.6 | 49.9 ± 2.7 | 37.4 ± 11.3* | ↓12.21% | 24.0 ± 4.4 | 19.82 ± 6.98c | 13.73 ± 5.24** | ↓45.30% |
M | 54.9 ± 6.5 | 47.2 ± 4.1 | 40.1 ± 4.1C | ↓5.87% | 23.7 ± 5.1 | 16.05 ± 2.85* | 14.98 ± 6.05** | ↓40.32% | |
L | 51.7 ± 1.1 | 45.3 ± 5.9 | 41.5 ± 3.6C | ↓2.58% | 24.7 ± 1.1 | 12.99 ± 3.66* | 12.82 ± 4.97** | ↓48.92% | |
PF90 | H | 50.7 ± 1.3 | 50.5 ± 4.8 | 40.2 ± 14.3C | ↓5.63% | 23.9 ± 1.3 | 16.31 ± 2.24* | 14.77 ± 3.73** | ↓41.16% |
M | 56.3 ± 2.0 | 52.4 ± 5.7 | 39.5 ± 5.0 C | ↓7.27% | 25.3 ± 2.0 | 15.13 ± 2.53* | 14.83 ± 2.29** | ↓40.92% | |
L | 52.2 ± 0.99 | 47.6 ± 7.5 | 39.8 ± 5.2C | ↓6.57% | 22.2 ± 0.99 | 16.74 ± 2.33c | 17.08 ± 3.56** | ↓31.95% |