Table 3 IC ₅₀ values obtained by using different cytotoxicity assays- MTT, NRU and LDH release

Culinary/medicinal mushroom

Pleurotus giganteus

Aqueous

4.07 ± 0.67^e

6.95 ± 1.00^g

-

2.16 ± 0.05^c

2.67 ± 0.47^d

-

Pleurotus pulmonarius

2.85 ± 0.06^cd

2.13 ± 0.87^cdef

-

1.75 ± 0.14^bc

2.60 ± 0.55^d

-

Lignosus rhinocerotis (sclerotium)

3.27 ± 0.77^d

2.72 ± 0.65^ef

-

5.63 ± 0.06^e

5.93 ± 0.05^f

-

Lignosus rhinocerotis

2.43 ± 0.12^c

1.75 ± 0.18^abc

-

5.23 ± 0.17^e

5.60 ± 0.1^f

-

(mycelium)

Hericium erinaceus

2.60 ± 0.52^cd

2.85 ± 0.56^e

-

3.43 ± 0.29^d

3.53 ± 0.06^e

-

Ganoderma lucidum

1.35 ± 0.03^a

1.52 ± 0.17^ab

2.20 ± 0.52^ab

1.19 ± 0.06^ab

1.35 ± 0.02^ab

1.50 ± 0.08^a

Ganoderma neo-japonicum

1.17 ± 0.006^a

1.11 ± 0.03^a

2.00 ± 0.53^ab

1.47 ± 0.37^ab

1.78 ± 0.56^bc

1.58 ± 0.44^a

Grifola frondosa

2.72 ± 0.08^cd

4.60 ± 1.10^f

-

6.67 ± 0.87^f

7.60 ± 0.1^g

-

Pleurotus giganteus

Ethanol

2.43 ± 0.10^c

2.81 ± 0.15^e

5.8 ± 0.10^c

1.66 ± 0.56^bc

1.96 ± 0.42^c

1.73 ± 0.48^a

Pleurotus pulmonarius

2.30 ± 0.72^bc

2.64 ± 0.16^def

2.53 ± 0.96^bc

1.27 ± 0.06^ab

1.48 ± 0.05^abc

1.67 ± 0.12^a

Hericium erinaceus

2.47 ± 0.50^c

1.61 ± 0.51^ab

2.10 ± 0.72^ab

1.31 ± 0.03^ab

1.84 ± 0.57^bc

1.47 ± 0.31^a

Cordyceps militaris

1.65 ± 0.015^ab

1.81 ± 0.10^abcd

2.37 ± 0.21^b

1.02 ± 0.08^a

1.10 ± 0.02^a

1.40 ± 0.29^a

Medicinal plant

Lycium barbarum

Aqueous

4.37 ± 1.00^e

6.96 ± 0.73^g

-

8.40 ± 0.72^g

7.86 ± 0.06^g

-

Gingko biloba

Ethanol

1.56 ± 0.08^ab

1.66 ± 0.11^ab

1.43 ± 0.39^a

1.56 ± 0.58^abc

1.37 ± 0.07^ab

1.78 ± 0.07^a

Curcumin

Compound

1.13 ± 0.01^a

1.15 ± 0.01^a

1.30 ± 0.16^a

1.16 ± 0.06^ab

1.23 ± 0.03^ab

1.60 ± 0.22^a