| NM | NM + AEHE | DM | DM + LAEHE | DM + HAEHE | DM + Gli |
---|
Day 0 | 105.6 ± 7.8 | 109.3 ± 8.6 | 278.9 ± 11.2a
| 286.3 ± 9.4a
| 291.0 ± 11.9a
| 289.1 ± 10.3a
|
Day 14 | 106.1 ± 8.1 | 103.4 ± 7.2 | 289.7 ± 10.4a
| 226.5 ± 8.7a,b,c
| 199.6 ± 12.5a,b,c
| 202.3 ± 8.5a,b,c
|
Day 28 | 107.3 ± 7.0 | 98.3 ± 9.9 | 296.1 ± 8.8a
| 163.2 ± 9.6a,b,c
| 135.4 ± 10.9a,b,c
| 129.3 ± 8.3a,b,c
|
- Values are expressed as mean ± SD in each group. NM group: normal control rats treated with vehicle alone; NM + AEHE group: normal control rats treated with AEHE (100 mg/kg b.w.); DM group: diabetic control rats treated with vehicle alone; DM + LAEHE group: diabetic rats were given AEHE (100 mg/kg b.w.); DM + HAEHE group: diabetic rats were given AEHE (200 mg/kg b.w.); DM + Gli group: diabetic rats were given glibenclamide (30 mg/kg b.w.). aindicates statistical significance of P < 0.05 compared to the NM group; bindicates statistical significance of P < 0.05 compared to the DM group. cindicates statistical significance of P < 0.05 compared to the same group at day 0.