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Table 1 In vitro activity of C. cajucara (red sacaca) essential oil and its purified 7-hydroxycalamenene-rich fraction against L. chagasi promastigotes and toxicity profile in mouse peritoneal macrophages

From: In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi

Substance tested L. chagasi Cytotoxicity [μg/mL]
MIC [μg/mL] IC50[μg/mL]
Essential oil 250 66.7 >500
7-hydroxycalamenene purified fraction 15.6 1.37 >500
Amphotericin B 0.625 0.01 14.6