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Table 5 IC 50 (μg/ml) values of crude and fractionated extracts of Alpinia pahangensis against selected cell lines

From: Antioxidant potential, cytotoxic activity and total phenolic content of Alpinia pahangensis rhizomes

Extract/ fraction

Inhibition concentration, IC50(μg/ml)

 

KB

MCF7

A549

Ca Ski

HCT 116

HT-29

MRC-5

Methanol

>100

>100

>100

>100

>100

>100

>100

Hexane

5.8 ± 0.1

22.0 ± 1.3

16.6 ± 0.2

18.4 ±0.2

9.1 ± 2.0

16.9 ± 0.5

17.3 ± 0.5

Ethyl acetate

10.2 ± 0.3

50.3 ± 0.3

25.9 ± 1.4

35.3 ± 2.0

19.9 ± 1.1

38.4 ± 0.4

44.0 ± 3.0

Water

>100

>100

>100

>100

>100

>100

>100

Doxorubicin

0.46 ± 0.02

0.088 ± 0.01

1.01 ± 0.02

0.31 ± 0.10

0.41 ± 0.07

0.56 ± 0.05

0.69 ± 0.05

  1. Each value is expressed as mean ± standand deviation of triplicate measurements.
  2. Data are expressed as IC50 in μg/ml which is the concentration of extract requires to inhibit cell growth by 50%).