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Table 3 Effects of OPLE on renal structure

From: Antioxidant and pro-oxidant effects of oil palm (Elaeis guineensis) leaves extract in experimental diabetic nephropathy: a duration-dependent outcome

 

Control

Diabetes control

Diabetes + OPLE 1000 mg kg-1

 

4 weeks

12 weeks

4 weeks

12 weeks

4 weeks

12 weeks

Glomerulosclerotic index

0.23 ± 0.03

0.34 ± 0.03

1.14 ± 0.06a

1.36 ± 0.04aa

0.68 ± 0.06a,b

1.62 ± 0.03aa

Tubulointerstitial fibrosis index

0.49 ± 0.05

0.61 ± 0.06

2.48 ± 0.18a

2.75 ± 0.16aa

1.03 ± 0.08b

3.05 ± 0.07aa

  1. Data are expressed as mean ± SEM of six experiments for each group. a P < 0.05; aa P < 0.01; vs. corresponding control; b P < 0.05, vs. corresponding diabetes control.