Antioxidant and pro-oxidant effects of oil palm (Elaeis guineensis) leaves extract in experimental diabetic nephropathy: a duration-dependent outcome

Table 1 Effects of OPLE on body and kidney weights, random blood glucose level and mean arterial pressure

	Control		Diabetes control		Diabetes + OPLE 1000 mg kg^-1
	4 weeks	12 weeks	4 weeks	12 weeks	4 weeks	12 weeks
Body weight (g)	365.0 ± 14.3	428.3 ± 13.0	309.2 ± 25.4	235.0 ± 14.6^aaa	291.7 ± 32.8	266.7 ± 15.2^aaa
Kidney weight (g 100 g^-1 body weight)	0.40 ± 0.01	0.32 ± 0.02	0.57 ± 0.03^aa	0.69 ± 0.02^aaa	0.56 ± 0.04^aa	0.64 ± 0.03^aaa
Glucose level (mmol l^-1)	4.7 ± 0.1	6.3 ± 0.2	30.7 ± 1.7^aaa	31.0 ± 1.2^aaa	27.0 ± 2.3^aaa	31.7 ± 0.8^aaa
Mean arterial pressure (mmHg)	113.2 ± 2.1	111.5 ± 2.9	115.3 ± 3.2	116.7 ± 3.3	115.0 ± 2.8	114.2 ± 2.5

Data are expressed as mean ± SEM of six experiments for each group. ^aa P < 0.01; ^aaa P < 0.001 vs. corresponding control.

ISSN: 2662-7671