Figure 3

Effect of IACFM on regional tissue perfusion following knee MCL injury. A: IACFM had no immediate effect on tissue perfusion ratios, with ratios immediately prior (PRE) and after (0) the first IACFM treatment, at 5, 10, 15 and 20 minutes post-treatment, and at 24 hours post-treatment not differing significantly from 1 (i.e. perfusion in IACFM-treated = perfusion in non-treated). B: IACFM significantly increased tissue perfusion over time. In addition to having increased perfusion when assessed at 24 hours after the 4th and last (9th) treatment (15 and 26 days post-MCL injury, respectively), IACFM treated hindlimbs had significantly greater perfusion when assessed one week following the final treatment session (32 days post-MCL injury). Data represent perfusion ratios (IACFM treated/non treated) between IACFM treated and non-treated hindlimbs, with error bars indicating the 95% confidence interval. Ratios >1 indicate greater perfusion in IACFM-treated hindlimbs. *p < 0.05, as determined by single sample t-tests with a population mean of 1.