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Table 1 Effect of i.p. administration of guava pomace extract (GPE) on a carrageenan-induced paw edema

From: Guava pomace: a new source of anti-inflammatory and analgesic bioactives

Groups

Dose (mg/kg)

Mean Edema ∆V mL (percent inhibition)

1 h

2 h

3 h

4 h

5 h

Control

-

0.10 ± 0.01

0.12 ± 0.01

0.14 ± 0.01

0.15 ± 0.01

0.09 ± 0.01

Indo

10

0.03 ± 0.01*

0.03 ± 0.01**

0.04 ± 0.01**

0.07 ± 0.01*

0.08 ± 0.01

(62)

(68)

(70)

(48)

(10)

GPE

300

0.05 ± 0.01*

0.05 ± 0.01*

0.08 ± 0.00*

0.09 ± 0.01

0.05 ± 0.01

(46)

(56)

(38)

(35)

(42)

GPE

100

0.05 ± 0.01*

0.08 ± 0.01*

0.10 ± 0.01

0.11 ± 0.01

0.10 ± 0.01

(51)

(42)

(27)

(4)

(13)

GPE

30

0.06 ± 0.01

0.07 ± 0.01

0.11 ± 0.01

0.09 ± 0.01

0.11 ± 0.03

(41)

(40)

(20)

(39)

(-)

  1. ∆V = the values represent the mean difference of paw volume between the basal measure and others measures (1, 2, 3, 4 and 5 h) ± S.E.M.; n = 5-6. *p < 0.05, **p < 0.01, significantly different when compared to control (ANOVA followed by Dunnett’s test).