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Table 4 Effect of Melastoma malabathricum leaves extract on antioxidant enzyme at end of the study

From: RETRACTED ARTICLE: Anti-diabetic, anti-oxidant and anti-hyperlipidemic activities of Melastoma malabathricum Linn. leaves in streptozotocin induced diabetic rats

S. no.

Biochemical parameter

Normal control

STZ-diabetic controla

STZ diabetes+

STZ diabetes+

STZ diabetes+

STZ diabetes+

MM Ib(100 mg/kg)

MM IIb(250 mg/kg)

MM IIIb(500 mg/kg)

Glibenclamideb(10 mg/kg)

1

SOD (U/mg of protein)

8.6 ± 0.509

3 ± 0.316***

4.2 ± 0.374*

6.2 ± .432**

8 ± 0.323***

7.8 ± 0.543***

2

CAT (U/mg of protein)

72.4 ± 1.631

38.6 ± 1.327***

46 ± 2.336*

56 ± 0.707**

68.8 ± 1.158***

67.4 ± 1.077***

3

GPx (mMH 2 O 2 decomposed/min)

47 ± 1.183

16.6 ± 0.927***

25 ± 0.707*

31.6 ± 1.077**

42 ± 0.712***

40.4 ± 0.927***

4

MDA (nmole/mg of protein)

0.34 ± 0.027

0.66 ± 0.028***

0.55 ± 0.017*

0.44 ± 0.011**

0.36 ± 0.012***

0.38 ± 0.016***

  1. All values represent mean ± SEM * P < 0.05; ** P < 0.01; *** P < 0.001; ANOVA, followed by Dunnett’s multiple comparison test.
  2. aCompared to vehicle control.
  3. bCompared to diabetic control.