Figure 21
Effect of Melastoma malabathricum Linn. (MM) on heart in different groups of rats: (A) Normal control: Normal control group shown normal histopathology of the heart there is no changes in interstitial space and intercalated disc. (B) Diabetic control: Diabetic control histopathology shown increased interstitial space, deposition of fats and distort the intercalated disc (yellow arrow) (C) MM I (100 mg/kg): Tested drug histopathology shown decreased interstitial space and having slightly distort intercalated disc (yellow arrow) (D) MM II (250 mg/kg): Tested drug histopathology shown less effect of interstitial space and intercalated disc (yellow arrow) (E) MM III (500 mg/kg): Tested drug histopathology shown normal heart like the glibenclamide (F) Glibenclamide (10 mg/kg): Glibenclamide treated drug shown the normal histopathology of heart. The samples were obtained from the same liver anatomical regions. For each group, 6 rats were examined and 50 pictures were taken. The above picture for each group was chosen randomly from the 80 pictures in this group. Original magnification, 40 ×.