Table 4 Mutagenic activity expressed by the mean number of revertants/plate ± standard deviation and mutagenicity ratio (in brackets) of stigmasterol, isolated substance of dichloromethane fraction of C. pallida leaves in S. typhimurium strain (TA98) in the absence (-S9) and in the presence of metabolism (+S9)
Stigmasterol | ||
|---|---|---|
Treatment | TA 98 | |
mg/plate | - S9 | +S9 |
DMSO | 16 ± 2 | 25 ± 2 |
0.02 | 16 ± 3 (1.0) | 31 ± 4 (1.2) |
0.04 | 17 ± 2 (1.1) | 23 ± 4 (0.9) |
0.09 | 15 ± 1 (0.9) | 27 ± 2 (1.1) |
0.18 | 17 ± 0 (1.1) | 22 ± 1 (0.9) |
0.5 | 19 ± 1 (1.2) | 30 ± 5 (1.2) |
Control + | 815 ± 21a | 1531 ± 36b |