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Table 1 Estrogenic activity expressed through the values of estradiol equivalents (EEQ) ± standard deviation of the extracts and EC 50 values of the ethanol extract of C. pallida , dichloromethane fraction and stigmasterol using a genetically modified strain of S. cerevisae BY4741

From: Estrogenic and mutagenic activities of Crotalaria pallida measured by recombinant yeast assay and Ames test

Samples

EEQ (nM) M ± SD

EC50(g/mL)

Ethanolic extract

14.3 ± 4.1

0.2

Dichloromethane fraction

89.0 ± 16.0

0.1

Stigmasterol

122.0 ± 11

10.5 × 10-7

17-β-estradiol

-

7.29 × 10-9

  1. EEQ, Values of estradiol equivalents (EEQ); M ± SD, Mean and standard deviation; EC 50 , Concentration of sample equivalent to 50% of the activity.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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