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Table 8 Effect of PN-M on charcoal-induced gut transit changes

From: The anti-shigellosis activity of the methanol extract of Picralima nitida on Shigella dysenteriae type I induced diarrhoea in rats

Group

Percentage of distance travelled by charcoal meal

Percentage of inhibition of the propulsive effect (%)

Vehicle

74.57 ± 9.90

0

Atropine sulphate (5 mg/kg)

40.32 ± 4.25**

45.93

PN (250 mg/kg)

58.27 ± 11.20*

21.86

PN (500 mg/kg)

60.54 ± 8.17*

18.81

  1. Data are means ± standard deviation (n = 6 per group). Values in the same column with superscript * are significantly different compared with control group (* p < 0.05; **p < 0.01).