The anti-shigellosis activity of the methanol extract of Picralima nitida on Shigella dysenteriae type I induced diarrhoea in rats

Table 3 The MIC and MBC values of the (M) extract of PN (fruit-rinds) against the microorganisms tested using microdilution assay

Microorganisms	P.a	S.fe	En.c	S.d	P.v	E.c	B.c	S.a	S.t	P.m	C.g	C.a
MIC (μg/ml)	50	200	>12800	800	0. 78	3.12	200	3.12	100	100	25	>12800
MBC(μg/ml)	1600	1600	>12800	6400	1.56	12.5	800	12.5	400	400	200	>12800

Values are the mean of three independent determination; the variation was less than 1/100 000. E.c: E coli; S.a: S.aureus; P.V: P.vulgaris; S.d: S.dysenteriae; En. c: E.cloacae; S.fe: S.feacalis; P.a: P.aeruginosa; P.m: P.mirabilis; S.t: S.typhi; B.c: B.cereus; C.a: C.albicans; C.g: C.glabrata. MIC: minimal inhibition concentration (μg/ml). MBC: minimal bactericidal concentration (μg/ml).

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