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Table 2 Genotoxic activity expressed by the mean and the standard deviation (SD) of the Olive Tail Moment (OTM) and percentage DNA in comet tail (% DNA) in MCF-7 BUS cells treated with nemorosone for 3 and 24 hours and controls

From: Evaluation of estrogenic, antiestrogenic and genotoxic activity of nemorosone, the major compound found in brown Cuban propolis

 

OTM

%DNA

OTM

%DNA

 

Mean ± SD

Mean ± SD

Mean ± SD

Mean ± SD

Treatments

  3 hours

 

  24 hours

 

Control

1.56±2.00

8.17±6.56

1.69±3.83

3.65±7.45

DMSO

1.84±2.57

8.26±7.67

2.05±3.29

4.98±3.52

10-9M

1.23±1.88

7.75±8.32

1.52±1.92

4.47±6.00

10-8M

1.51±1.75

9.45±8.32

2.05±3.78

5.77±5.89

10-7M

1.35±1.47

6.17±7.98

2.35±1.98

6.17±5.12

10-6M

1.51±1.89

9.01±8.02

2.32±2.96

6.17±4.00

10-5M

1.11±1.73

7.67±7.98

0.94±1.60

2.48±6.76

  1. Negative control: Culture Medium (DMEM).
  2. DMSO: Solvent control (0.01%).
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BMC Complementary Medicine and Therapies

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