Skip to main content

Table 3 Changes in the organ weight of rats Wistar after acute oral treatment with Dioscorea villosa at a daily dose of 5 g/Kg (single dose)

From: Bioassay-guided evaluation of Dioscorea villosa – an acute and subchronic toxicity, antinociceptive and anti-inflammatory approach

    Groups

Organs

FC

FT

MC

MT

Heart

0.4729 ± 0.015

0.4543 ± 0.011

0.4114 ± 0.010

0.3929 ± 0.015

Lungs

0.7343 ± 0.024

0.6700 ± 0.027

0.5529 ± 0.023

0.4786 ± 0.025

Liver

3.309 ± 0.1047

3.506 ± 0.1595

2.947 ± 0.080

2.960 ± 0.1238

Brain

0.7671 ± 0.022

0.8757 ± 0.022**

0.4914 ± 0.027

0.5414 ± 0.031

Kidneys

0.8071 ± 0.021

0.8271 ± 0.030

0.8329 ± 0.043

0.7671 ± 0.030

Stomach

0.8671 ± 0.032

0.7771 ± 0.015*

0.6571 ± 0.024

0.5686 ± 0.030*

Uterus/ovaries

0.4629 ± 0.089

0.7486 ± 0.097

-

-

Pancreas

0.4843 ± 0.092

0.5614 ± 0.060

0.3371 ± 0.097

0.3786 ± 0.043

  1. FC control female, FT treated female, MC control male, MT treated male. Data are expressed as mean ± S.D., n = 6; * Significant difference from control group ( *p < 0.05, **p < 0.01 and ***p < 0.001) (test t).