Figure 7

Sensitization by PPD is mediated through altering cell cycle progression and apoptosis. K562 cells were exposed to Cisplatin (A and B) or PPD (C and D) at 0, 25 or 50 μM with or without 0.25 μM Doxorubicin for 48 hr. Then they were fixed with ethanol, stained with propidium iodide and analyzed using flow cytometry. All experiments were repeated three times with similar results.