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Table 3 Differential protein levels in Phyllanthus -treated dengue-infected Vero cells

From: Effects of cocktail of four local Malaysian medicinal plants (Phyllanthus spp.) against dengue virus 2

ID

Accession

Score

Possible proteins

C

C + P

C + V

C + V + P

Viral Entry

3

Q28222.1

1059

Heat Shock Protein 70 (Hsp70)

192.1

200.2

312.2

234.3

4

Q28222.1

768

Heat Shock Protein 70 (Hsp 70)

199.5

287.4

419.3

282.2

5

Q2IBA6.1

483

Hepatocyte Growth Factor Receptor (HGFR)

192.7

200.4

313.4

259.7

12

Q2IBA6.1

136

Hepatocyte Growth Factor Receptor (HGFR)

222.5

0.0

313.2

218.2

14

Q2IBA6.1

178

Hepatocyte Growth Factor Receptor (HGFR)

206.3

0.0

312.5

200.1

22

Q2IBA6.1

139

Hepatocyte Growth Factor Receptor (HGFR)

231.9

237.1

331.3

225.5

39

Q2IBA6.1

132

Hepatocyte Growth Factor Receptor (HGFR)

203.8

206.7

390.0

212.9

41

Q2IBA6.1

120

Hepatocyte Growth Factor Receptor (HGFR)

211.0

224.2

333.2

221.6

Viral Uncoating

37

AAT48107.1

132

Trim 1

187.4

198.8

366.1

535.3

Viral Transcription and Translation

7

ABB92440.1

489

RNA Binding Motif 1 (RBMI)

197.6

0.0

412.3

222.2

8

ABB92440.1

383

RNA Binding Motif 1 (RBMI)

206.0

0.0

362.1

226.7

10

ABB92440.1

141

RNA Binding Motif 1 (RBMI)

213.8

0.0

372.7

221.2

24

ABB92440.1

77

RNA Binding Motif 1 (RBMI)

180.4

0.0

362.4

181.7

42

ABB92440.1

633

RNA Binding Motif 1 (RBMI)

202.9

222.2

424.2

313.3

27

NP_739587.2

173

Nonstructural protein NS3

0.0

0.0

312.3

123.2

35

2FOM_B

151

Chain B, Dengue virus NS2bNS3 Protease

0.0

0.0

262.8

123.2

38

Q7YR26.1

63

DNA topoisomerase 1 (DNA Topo 1)

202.9

211.3

373.2

229.2

43

Q5XXB5.1

84

DNA mismatch repair protein Msh2

201.1

212.2

415.2

311.3

44

Q5XXB5.1

129

DNA mismatch repair protein Msh2

209.1

205.3

394.2

213.3

47

Q5RF69

185

Histidine triad nucleotide-binding protein 1

194.4

189.1

393.4

194.0

Viral Post-translational Modification

25

Q4VIT5.1

346

Calreticulin

188.0

200.4

333.3

213.2

Glucose Uptake and Glycolytic Enzymes

6

Q8CGV6

559

Glyceraldehyde-3-phosphate dehydrogenase (G3PD)

213.9

231.3

524.1

313.2

49

AAF17105.1

151

Polysialyltransferase

207.1

212.3

313.7

232.3

Cytoskeletal assembly

1

Q76N69.1

846

Beta actin

168.8

185.3

512.2

273.2

  1. C = cells only; C + P = Phyllanthus-treated cells; C + V = dengue-infected cells; C + P + V = Phyllanthus treated dengue infected cells.