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Table 3 Effects of DES and omeprazole, administered intraduodenally, on the biochemical parameters of gastric juice obtained from pylorus-ligature in rats

From: Gastroprotective effect of desmosdumotin C isolated from Mitrella kentii against ethanol-induced gastric mucosal hemorrhage in rats: possible involvement of glutathione, heat-shock protein-70, sulfhydryl compounds, nitric oxide, and anti-Helicobacter pylori activity

Animal group

treatment 5 ml/kg

Volume (ml)

pH

Acid output [H+] mEq/L

A

Control group (5% Tween 80)

3.5 ± 0.015

3.83 ± 0.088

95 ± 0.88

B

Omeprazole (30 mg/kg)

2.71 ± 0.015*

6.17 ± 0.015*

83 ± 1.15*

C

DES (5 mg/kg)

3.1 ± 0.12* $

4.92 ± 0.012*$

92 ± 0.58*$

D

DES (10 mg/kg)

2.87 ± 0.12*

5.98 ± 0.01*

89 ± 0.88*$

E

DES (20 mg/kg)

2.94 ± 0.008*

5.96 ± 0.01*$

90 ± 0.33*$

  1. Results are expressed as mean ± S.E.M. (n = 6 rats).* indicate p < 0.05 compared to control group. $ indicate p < 0.05 compared to omeprazole.