Figure 3

Effect of the CTCM on the histamine and IL-4 levels in the BALF. CTCM treatment before OVA challenge reduced the histamine and IL-4 levels in the BALF 5 min after OVA challenge (one-way ANOVA with a Duncan post-hoc test, **P <0.01: SGP_MO vs. SGP_O). Each group represents the mean of the data from 10 animals and the vertical bars represent the standard deviation. (A) Histamine and (B) IL-4. NSGP_O: unsensitized guinea pigs challenged with OVA by nebulization; SGP_O: sensitized guinea pigs challenged with OVA by nebulization; SGP_MO: sensitized guinea pigs treated with 0.06 g/ml nebulized CTCM for 5 min, followed by OVA challenge by nebulization (at 5 min post-CTCM nebulization).