Figure 1
The CTCM had a bronchodilator effect. Guinea pigs were treated with a nebulized form of the CTCM, and the pulmonary resistance (RL) was significantly reduced (to 61.0 ± 0.01% of the baseline) 20 min post-CTCM treatment, while no change was seen in the animals treated with saline. (A) Overview of the 7-hr period. Comparison between the NSGP_S and NSGP_M groups. (B) Comparison of the different groups of sensitized animals in the first hour (repeated measures ANOVA with a Mauchly post-hoc test; **P <0.01). NSGP_S: unsensitized guinea pigs treated with saline by nebulization; NSGP_M: unsensitized guinea pigs treated with 0.06 g/ml CTCM for 5 min by nebulization.