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Table 2 Effects of XJEK on cardiac function in 2K1C hypertensive rats (mean ± SD, n = 8 ~ 11)

From: Effects of traditional Chinese medicine Xin-Ji-Er-Kang formula on 2K1C hypertensive rats: role of oxidative stress and endothelial dysfunction

Group

LVSP(mmHg)

LVEDP(mmHg)

+dP/dtmax(mmHg/s)

-dP/dtmax(mmHg/s)

Sh-Op

113.07 ±11.66

27.56 ±9.11

7672.57 ± 2158.28

−7046.04 ±1501.92

Model

149.21 ± 20.68**

46.93 ± 19.92**

8477.46 ± 1123.74

−7483.98 ±1122.43

XJEK

    

6 g/kg

121.34 ± 16.99##

40.88 ±7.40

7358.72 ± 1389.27

−7679.91 ±1906.72

12 g/kg

115.61 ± 14.16##

35.66 ±9.49

7140.11 ± 2493.83

−7666.94 ±1235.32

24 g/kg

113.60 ± 15.86##

37.93 ±4.28

6310.59 ± 1588.00##

−7015.20 ± 1162 .04

Fosinopril

    

15 mg/kg

110.53 ± 11.26##

36.65 ±12.28

6514.32 ±2417.83#

−7152.12 ±1789.97

  1. LVSP left ventricular systolic pressure, LVEDP left ventricular end-diastolic pressure, +dp/dt max maximal rate of left ventricular systolic pressure, -dp/dtmax maximal rate of left ventricular diastolic pressure. ** P < 0.01 vs Sh-Op group; # P < 0.05, ## P < 0.01 vs model group.