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Table 2 IC 50 of CACF or doxorubicin in melanoma A375 cells and normal primary melanocytes determined by MTT assays after 24 and 48 h treatment

From: Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways

 

CACF

Doxorubicin

IC50(mean ± SD) μg/mL

IC50(mean ± SD) μg/mL

 

24 h

48 h

24 h

48 h

A375

9.3 ± 2.5

8.5 ± 1.2

7.6 ± 0.8

6.2 ± 1.5

Primary melanocytes

24.3 ± 4.6

21.5 ± 3.1

8.5 ± 2.5

7.2 ± 2.2