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Table 2 GI 50 , TGI and LC 50 (μg/mL) for EAD and Dox

From: The flavonoid content and antiproliferative, hypoglycaemic, anti-inflammatory and free radical scavenging activities of Annona dioica St. Hill

  EAD Dox
Cancer cell lines GI50 TGI LC50 GI50 TGI LC50
U251 (glioma) 83.47    5.07 23.45  
UACC-62 (melanoma) > 100    0.06 0.86  
MCF7 (breast) 11.10 > 100   0.14 24.52  
NCI/ADR-RES (ovarian resistance) 1.95    1.74 23.92  
786-0 (renal) > 100    0.22 1.51  
NCI-H460 (lung) 0.03 > 100   0.05   
OVCAR-3 (ovarian) 6.38    0.30 1.72  
HT29 (colon) 0.10 4.10 > 100 2.12 7.31 20.86
K-562 (leukemia) 31.13    0.90   
Vero     1.40 11.36  
  1. EAD (crude methanol extract); dox (doxorubicin); GI50 (growth inhibitory activity); TGI (cytostatic activity); LC50 (cytotoxic activity); IC50 >100 (μg/mL) was considered not active.