Skip to main content

Advertisement

Table 1 Histone modifications and the associated chromatin conformation

From: Histone modifications and traditional Chinese medicinals

Histone/DNA modification Enzymes Position/abbreviation* Conformation Reference
cytosine methylation DNA methyltransferase DNMT heterochromatic [24]
histone acetylation histone acetyltransferase HAT euchromatic [2]
histone deacetylation histone deacetylase HDAC heterochromatic [2]
histone methylation histone methyltransferase H3K4 euchromatic [25]
H3K36 euchromatic
H3K79 euchromatic
H3R17 euchromatic
H3K9 heterochromatic
H3K27 heterochromatic
H4K20 heterochromatic
histone demethylation histone demethylase H3K4i heterochromatic [26]
H3K36i heterochromatic
H3R2i heterochromatic
H4R3i heterochromatic
H3K27i euchromatic
histone phosphorylation mitogen- and stress-activated protein kinase (MSK), I kappa B alpha kinase (IKK) H3S10 euchromatic [27]
histone de-phosphorylation MAP kinase phosphatase (MKP) H3S10i heterochromatic [28]
ATP-dependent chromatin remodeling ATP-dependent chromatin remodeling complex ATP hetero- or euchromatic [29]
  1. * K Lysine, R Arginine, S serine, H3K4 H3K4 methylation, H3K4i H3K4 demethylation, H3S10 H3S10 phosphorylation, H3S10i H3S10 dephosphorylation.