Table 1 Effect of genistein treatment on histologic changes in the mouse small intestine 3.5 d after 10Â Gy irradiation
From: Protective effect of genistein on radiation-induced intestinal injury in tumor bearing mice
| Â | Sham | Genistein | IR (10Â Gy) | Genistein + IR (10 Gy) |
|---|---|---|---|---|
Number of crypts/circumstance | 120.7 ± 2.5 | 109.1 ± 8.2 | 14.6 ± 2.5 | 24.6 ± 2.6* |
Number of villi/circumstance | 40.6 ± 2.7 | 41.1 ± 3.8 | 32.6 ± 1.8 | 35.5 ± 1.7 |
Villus height (μm) | 398.6 ± 13.8 | 378.4 ± 18.1 | 124.0 ± 7.2 | 186.2 ± 12.5** |
Crypt depth (μm) | 89.6 ± 5.8 | 90.1 ± 4.8 | 98.9 ± 4.2 | 136.8 ± 7.1** |
Basal lamina length (μm/10 enterocytes) | 44.6 ± 3.0 | 41.4 ± 6.2 | 123.1 ± 10.4 | 95.7 ± 5.9* |