Figure 4From: Protective effect of genistein on radiation-induced intestinal injury in tumor bearing mice Photomicrographs of progenitor cells in the jejunum circumference stained with an antibody for Ki-67. (A and B) Sham control group, (C and D) irradiation control group, and (E and F) genistein-pretreatment group 3.5 d after 10 Gy irradiation. Most of the Ki-67-positive cells were detected in the jejunal crypts. The number of Ki-67-positive cells decreased in irradiated mice, which corresponded to surviving crypts at 3.5 d after 10 Gy irradiation. However, higher Ki-67 expression was observed in crypts of increased depth in irradiated groups compared with the sham control group. A greater number of Ki-67-positive cells was observed in the genistein-treated group than in the irradiation control group at this magnification. (A, C, and E) magnification × 100. (B, D, and F) magnification × 400.Back to article page