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Figure 2 | BMC Complementary and Alternative Medicine

Figure 2

From: Protective effect of genistein on radiation-induced intestinal injury in tumor bearing mice

Figure 2

Photomicrographs of the apoptotic changes in the jejunal crypts revealed by TUNEL assay 12 h after 5 Gy gamma irradiation. (A) Sham control, (B) irradiation control, and (C) genistein treatment prior to irradiation. (A) A small number of crypt cells exhibited apoptosis in the sham control mice. (B) Irradiation increased the expression of apoptotic nuclei in the crypt cells of the jejunum. (C) The number of apoptotic cells decreased slightly in the group treated with genistein compared with the irradiation control group (A, B, and C). (D) Bar graphs showing the number of apoptotic cells per crypt in the jejunum sections, as determined by the TUNEL method, in the sham control group, irradiation control group, and genistein-pretreated group exposed to 5 Gy irradiation. The data are shown as the means ± SEM for 5 mice in each group. *P < 0.05 as compared with the irradiation control group.

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