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Table 2 Intracellular fluorescence intensity of Rh-123 accumulation in H22/ADM cells (n = 6)

From: Effects of Astragalus polysaccharides on P-glycoprotein efflux pump function and protein expression in H22 hepatoma cells in vitro

Group

Fluorescence intensity (mean ± SD)

 

24 h

48 h

72 h

RFP 10 μmol/L

87.49 ± 1.26

133.71 ± 1.59

131.41 ± 1.54

Control group

114.77 ± 1.16

198.51 ± 0.69

136.18 ± 1.32

APS 0.8 mg/L

135.52 ± 0.92

255.14 ± 0.61

137.40 ± 2.01

APS 4 mg/L

257.38 ± 0.97

266.32 ± 2.03

250.32 ± 1.80

APS 20 mg/L

357.34 ± 0.80

285.75 ± 1.30

367.35 ± 1.31

APS 100 mg/L

342.83 ± 0.94

307.42 ± 1.12

460.04 ± 1.74

APS 500 mg/L

701.30 ± 1.14

345.27 ± 1.84

458.43 ± 0.63

VER 10 μmol/L

928.04 ± 1.17

706.04 ± 2.02

657.91 ± 1.28

  1. P < 0.05, vs. Control group (24 h); P < 0.05, vs. Control group (48 h); P < 0.05, vs. Control group (72 h).