Skip to main content

Table 3 Hematological values following 13 weeks of daily oral administration of NS in male and female rats

From: Assessment of anti-depressant effect of nelumbinis semen on rats under chronic mild stress and its subchronic oral toxicity in rats and beagle dogs

Hematology values

Dose (mg/kg)

Sex

WBC

RBC

HGB

HCT

MCV

MCH

MCHC

RDW

HDW

PLT

  

(103/μl)

(106/μl)

(g/dl)

(%)

(fl)

(pg)

(g/μl)

(%)

(g/dl)

(103/μl)

0

M

9.1 ± 1.1

9.2 ± 0.3

16.1 ± 0.5

51.3 ± 1.6

56.1 ± 1.3

17.6 ± 0.5

31.4 ± 0.4

12.0 ± 0.3

2.1 ± 0.1

1140 ± 98

 

F

4.9 ± 1.6

7.8 ± 0.3

14.6 ± 0.4

47.0 ± 1.3

60.3 ± 1.1

18.7 ± 0.6

31.0 ± 0.7

10.8 ± 0.2

1.9 ± 0.1

1147 ± 106

500

M

8.2 ± 1.5

9.0 ± 0.2

16.0 ± 0.4

51.5 ± 0.9

57.2 ± 1.3

17.9 ± 0.5

31.2 ± 0.5

12.3 ± 0.2 *

2.25 ± 0.1 **

1066 ± 115

 

F

4.7 ± 1.6

7.9 ± 0.2

14.5 ± 0.4

47.1 ± 1.3

59.4 ± 0.6

18.3 ± 0.4

30.8 ± 0.6

10.8 ± 0.4

2.0 ± 0.2

1111 ± 64

1000

M

9.1 ± 1.4

8.9 ± 0.3

15.8 ± 0.7

50.7 ± 1.7

56.7 ± 1.0

17.7 ± 0.5

31.3 ± 0.4

12.3 ± 0.4

2.2 ± 0.1 *

1121 ± 45

 

F

4.2 ± 2.1

7.9 ± 0.2

14.6 ± 0.3

47.4 ± 1.1

60.4 ± 1.7

18.5 ± 0.6

30.7 ± 0.3

10.9 ± 0.4

1.9 ± 0.2

1081 ± 77

2000

M

9.3 ± 2.1

9.3 ± 0.4

16.0 ± 0.5

51.6 ± 1.8

55.7 ± 2.0

17.3 ± 0.7

31.0 ± 0.4

12.4 ± 0.4 *

2.2 ± 0.1 **

1177 ± 143

 

F

4.8 ± 1.8

7.7 ± 0.3

14.4 ± 0.5

17.0 ± 1.4

60.8 ± 1.0

18.6 ± 0.3

30.6 ± 0.3

10.8 ± 0.4

2.0 ± 0.2

1063 ± 113

  1. HCT = Hematocrit, HDW = Hb conc. Distribution width, HGB = Hemoglobin concentration, MCH = Mean corpuscular hemoglobin, MCHC = Mean corpuscular hemoglobin concentration, MCV = Mean corpuscular volume, PLT = Platelet, RBC = Red blood cell, RDW = Red cell distribution width, WBC = White blood cell.
  2. *P < 0.05, **P < 0.01 compared to the control group.