Dietary intervention with narrow-leaved cattail rhizome flour (Typha angustifolia L.) prevents intestinal inflammation in the trinitrobenzenesulphonic acid model of rat colitis

Table 2 Effects of different treatments on damage score, extension of lesion, changes in colon weight, adherences to adjacent organs and microscopic score

Experimental Groups	Score^a(0–10)	Extension of lesion^b(cm)	Colon weight^b(mg/cm)	Adherence(%)	Microscopic Score (0-27)^a
Non-colitic groups
Non treated	0***	0**	112.68 ± 6.28**	0**	0**
20% diet	0***	0**	113.63 ± 5.56**	0*	0**
Colitic groups
TNBS-Control	7 (4–8)	3.04 ± 0.33	260.63 ± 37.62	60	10.5 (5–19)
5% diet	6 (0–7)	1.67 ± 0.42*	156.67 ± 16.76*	15*	8 (5–15)
10% diet	5 (4–6)	1.45 ± 0.29*	169.24 ± 6.12*	0*	5 (3–11)
20% diet	6 (4–8)	2.17 ± 0.36	204.75 ± 22.81	85	4 (2–10)
5% diet + prednisolone	7 (5–10)	3.24 ± 0.59	196.73 ± 23.22	15*	5 (2–14)
10% diet + prednisolone	6 (5–7)	2.43 ± .029	156.01 ± 9.87*	45	7 (2–11)
20% diet + prednisolone	6 (0–8)	2.41 ± 0.68	258.04 ± 63.77	45	5 (1–9)
prednisolone	3 (0–4)*	1.40 ± 0.27*	162.20 ± 8.14*	45	11.0 (8–14)

^a Score and microscopic score data are expressed as median (range) and were statically evaluated by non-parametric Kruskal-Wallis test; ^b Extension of lesion and colonic weight data are expressed as mean ± SEM values and differences were assessed using ANOVA was followed by post hoc test of Dunnet; Adherence was expressed in percentage and was analyzed with the χ² test. *P < 0.05, P < 0.01 and P < 0.001 versus TNBS control group.

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