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Table 4 Effect of Qur and/or Arg treatment on serum creatinine, urea, and uric acid levels in intoxicated rats with a high dose of n-ZnO particles

From: Role of quercetin and arginine in ameliorating nano zinc oxide-induced nephrotoxicity in rats

Parameters

Control

n-ZnO

Qur

Arg

Qur + Arg

Creatinine (mg/dl)

0.4 ± 0.075

0.63 ± 0.087 a

0.51 ± 0.066

0.50 ± 0.033 *

0.50 ± 0.045*

Urea (mg/dl)

21.4 ± 4.88

35.2 ± 5.88 b

29.8 ± 4.57

28.8 ± 2.02

28.2 ± 5.21

Uric acid (mg/dl)

2.1 ± 0.55

3.02 ± 0.53

2.84 ± 0.98

2.93 ± 0.61

2.36 ± 0.55

  1. Data are presented as mean ± S.D. from 10 rats, a P ≤ 0.001, b P ≤ 0.01 compared with the normal group, * P ≤ 0.05 compared with the n-ZnO-intoxicated group, respectively, using ANOVA followed by Bonferroni as a post-ANOVA test.