Role of quercetin and arginine in ameliorating nano zinc oxide-induced nephrotoxicity in rats

Table 2 Effect of Qur and/or Arg treatment on serum inflammatory marker levels in intoxicated rats with a high dose of n-ZnO particles

Parameters	Control	n-ZnO	Qur	Arg	Qur + Arg
TNF- α (Pg/ml)	242.7 ± 6.1	371.7 ± 6.1^a	293.6 ± 4.3^*b	322.18 ± 1.9^*b#	314.1 ± 2.9^*b#
CRP (ng/ml)	3.16 ± 0.1	4.6 ± 0.11 ^a	2.9 ± 0.05^*	3.0 ± 0.07^*	3.7 ± 0.055^{*b# #}
IL-6 (ng/ml)	31 ± 2.098	49.57 ± 1.01 ^a	39.41 ± 0.62^a*	41.80 ± 0.28a^*#	44.94 ± 1.02a^*###

Data are presented as mean ± S.D. for 10 rats, ^a P ≤ 0.001, ^b P ≤ 0.01 compared with the normal group, ^* P ≤ 0.001 compared with the n-ZnO intoxicated-group, ^# P ≤ 0.05, ^## P ≤ 0.01, ^### P ≤ 0.01 compared with the combination group, respectively, using ANOVA followed by Bonferroni as a post-ANOVA test.

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