| WKY | SHR | SHR-Rg1(5) | SHR-Rg1(10) | SHR-Rg1(20) |
---|---|---|---|---|---|
SBP(mmHg) | 133.7 ± 2.2 | 184.5 ± 3.4### | 186.0 ± 2.4### | 183.5 ± 3.3### | 183.0 ± 4.2### |
DBP(mmHg) | 97.5 ± 2.0 | 139.0 ± 3.0### | 138.0 ± 2.4### | 139.1 ± 2.8### | 133.8 ± 3.9### |
HR (bpm) | 360.6 ± 14.0 | 393.6 ± 12.5# | 366.7 ± 13.7 | 412.6 ± 8.9 | 433.5 ± 9.3* |
MAP(mmHg) | 111.5 ± 6.3 | 170.1 ± 16.7### | 181.6 ± 14.0### | 175.4 ± 37.4### | 193.7 ± 10.4### |
EDP(mmHg) | 6.1 ± 1.7 | 7.5 ± 3.0 | 3.1 ± 1.0 | 4.8 ± 3.9 | 5.5 ± 1.8 |
LVSP(mmHg) | 120.9 ± 7.1 | 207.1 ± 17.9### | 213.7 ± 21.1### | 224.3 ± 35.4### | 217.5 ± 16.8### |
+dP/dtmax (mm HgS-1) | 8661.1 ± 717.7 | 11735.7 ± 635.8## | 13063.6 ± 470.8### | 12651.9 ± 803.0## | 12636.7 ± 514.7### |
-dP/dtmax (mm HgS-1) | −7514.6 ± 626.0 | −11272.1 ± 872.8## | −12410.0 ± 595.7### | −11330.2 ± 722.8### | −11464.1 ± 534.8### |
HW/BW(mg/g) | 2.9 ± 0.2 | 3.9 ± 0.05# | 3.8 ± 0.08# | 3.8 ± 0.07# | 3.6 ± 0.06# ** |