Table 2 IC50 values of C.spinosa fractions and drugs in tumor cell lines and normal cells (gingival fibroblasts and PBMC) estimated using the MTT assay. *Concentration (μg/ml) ± SE
Cell line/Treatment | K562 | Fibroblast | PBMC |
|---|---|---|---|
S2Et | > 125* | > 125* | > 125* |
P2Et | 44.50* ± 4.05 | 64.30* ± 1.00 | > 125* |
Aqueous | > 125* | > 125* | > 125* |
Etoposide | 15.60* ± 0.31 | > 200* | > 200* |
Doxorubicin | 0.24* ± 0.14 | 5.80* ± 0.40 | 2023* ± 0.50 |
Taxol | 1.14* ± 0.15 | - | - |
Vincristine | 1.07* ± 0.28 | 0.07* ± 2.40 | 0.18* ± 2.00 |
Camptothecin | 14.10* ± 3.70 | - | - |