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Table 2 IC50 values of C.spinosa fractions and drugs in tumor cell lines and normal cells (gingival fibroblasts and PBMC) estimated using the MTT assay. *Concentration (μg/ml) ± SE

From: A gallotannin-rich fraction from Caesalpinia spinosa (Molina) Kuntze displays cytotoxic activity and raises sensitivity to doxorubicin in a leukemia cell line

Cell line/Treatment K562 Fibroblast PBMC
S2Et > 125* > 125* > 125*
P2Et 44.50* ± 4.05 64.30* ± 1.00 > 125*
Aqueous > 125* > 125* > 125*
Etoposide 15.60* ± 0.31 > 200* > 200*
Doxorubicin 0.24* ± 0.14 5.80* ± 0.40 2023* ± 0.50
Taxol 1.14* ± 0.15 - -
Vincristine 1.07* ± 0.28 0.07* ± 2.40 0.18* ± 2.00
Camptothecin 14.10* ± 3.70 - -