Table 4 Mutagenic activity of extracts from A. salicina by the S. typhimurium TA98 and TA102 assay systems in the presence and absence of the metabolic activation system (S9)
TA98 | TA102 | ||||
|---|---|---|---|---|---|
Extracts | Dose (µg/plate) | -S9 | +S9 | -S9 | +S9 |
Spontaneous | - | 27 ± 6 | 36 ± 2 | 175 ± 10 | 235 ± 12 |
PC | - | 723 ± 21 | 122 ± 11 | 1721 ± 24 | 652 ± 10 |
Aqueous extract | 50 | 22 ± 2 | 42 ± 4 | 223 ± 11 | 387 ± 07 |
|  | 250 | 24 ± 2 | 75 ± 5 | 234 ± 12 | 398 ± 12 |
|  | 500 | 24 ± 3 | 85 ± 5 | 245 ± 09 | 477 ± 21 |
TOF extract | 50 | 23 ± 3 | 54 ± 8 | 214 ± 08 | 345 ± 09 |
|  | 250 | 25 ± 4 | 72 ± 10 | 221 ± 12 | 354 ± 05 |
|  | 500 | 29 ± 3 | 102 ± 13 | 223 ± 11 | 377 ± 05 |
Methanolic extract | 50 | 24 ± 4 | 44 ± 14 | 221 ± 10 | 276 ± 11 |
|  | 250 | 31 ± 5 | 74 ± 13 | 242 ± 05 | 356 ± 12 |
|  | 500 | 55 ± 7 | 95 ± 5 | 232 ± 08 | 455 ± 15 |