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Table 2 Changes of serum liver function and liver tissue hydroxyproline content in each group (mean S.D.)

From: Ingredients of Huangqi decoction slow biliary fibrosis progression by inhibiting the activation of the transforming growth factor-beta signaling pathway

group

n

TBil(mg/dl)

Alb(g/l)

ALT(u/L)

Hyp (μg/g wet liver)

sham control group

8

0.90 ± 0.28##

25.62 ± 1.98##

12.92 ± 1.13##

164.90 ± 12.41##

1 week BDL alone group

8

5.24 ± 0.85**#

23.10 ± 2.45##

69.18 ± 2.82**##

292.96 ± 93.68**##

2 week BDL alone group

8

5.51 ± 0.80**#

20.97 ± 0.39**##

31.68 ± 4.00**##

326.93 ± 14.45**##

3 week BDL alone group

8

5.58 ± 0.27**

20.12 ± 1.57**##

38.96 ± 8.15**##

804.70 ± 35.50**##

4 week BDL alone group

8

6.16 ± 0.95**

16.4 ± 3.15**##

56.83 ± 9.96**

808.37 ± 65.93**##

5 week BDL alone group

10

6.72 ± 0.24**

12.48 ± 3.22**

56.38 ± 5.79**

1069.03 ± 69.27**

IHQD group

14

3.08 ± 0.60**##

15.18 ± 2.99**#

48.81 ± 3.57**#

853.85 ± 21.4**##

  1. Note: Compared with sham control group, *p < 0.05, **p < 0.01; compared with 5 week BDL alone group, #p < 0.05, ##p < 0.01. TBil total bilirubin, ALT alanine aminotransferase, Alb albumin, Hyp hydroxyproline